Rapid and Efficient Conversion of Integration-Free Human Induced Pluripotent Stem Cells to GMP-Grade Culture Conditions

Data suggest that clinical applications of human induced pluripotent stem cells (hiPSCs) will be realized. Nonetheless, clinical applications will require hiPSCs that are free of exogenous DNA and that can be manufactured through Good Manufacturing Practice (GMP). Optimally, derivation of hiPSCs sho...

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Bibliographic Details
Main Authors: Durruthy-Durruthy, Jens, Briggs, Sharon F., Awe, Jason, Ramathal, Cyril Y., Karumbayaram, Saravanan, Lee, Patrick C., Heidmann, Julia D., Clark, Amander, Karakikes, Ioannis, Loh, Kyle M., Wu, Joseph C., Hoffman, Andrew R., Byrne, James, Reijo Pera, Renee A., Sebastiano, Vittorio
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981795/
https://ncbi.nlm.nih.gov/pubmed/24718618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094231
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