Immune evasion by oncogenic proteins of acute myeloid leukemia

PML-RARA and AML1-ETO are important oncogenic fusion proteins that play a central role in transformation to acute myeloid leukemia (AML). Whether these fusion proteins render the tumor cells with immune evasion properties is unknown. Here we show that both oncogenic proteins specifically downregulat...

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Main Authors: Elias, Shlomo, Yamin, Rachel, Golomb, Lior, Tsukerman, Pinchas, Stanietsky-Kaynan, Noah, Ben-Yehuda, Dina, Mandelboim, Ofer
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981677/
https://ncbi.nlm.nih.gov/pubmed/24449212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-526590
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