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Immune evasion by oncogenic proteins of acute myeloid leukemia

PML-RARA and AML1-ETO are important oncogenic fusion proteins that play a central role in transformation to acute myeloid leukemia (AML). Whether these fusion proteins render the tumor cells with immune evasion properties is unknown. Here we show that both oncogenic proteins specifically downregulat...

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Detalhes bibliográficos
Main Authors: Elias, Shlomo, Yamin, Rachel, Golomb, Lior, Tsukerman, Pinchas, Stanietsky-Kaynan, Noah, Ben-Yehuda, Dina, Mandelboim, Ofer
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981677/
https://ncbi.nlm.nih.gov/pubmed/24449212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-526590
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