Impaired interleukin-3 (IL-3) response of the A/J mouse is caused by a branch point deletion in the IL-3 receptor alpha subunit gene.

Interleukin-3 (IL-3) alone does not support hematopoietic colony formation of bone marrow cells from the A/J mouse. To elucidate the molecular lesion in A/J mice, we examined expression of the alpha and beta subunits of the IL-3 receptor (IL-3R). While IL-3R beta was normally expressed, IL-3R alpha...

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Bibliographische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Ichihara, M, Hara, T, Takagi, M, Cho, L C, Gorman, D M, Miyajima, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1995
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398166/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7889941/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07075.x
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