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Impaired interleukin-3 (IL-3) response of the A/J mouse is caused by a branch point deletion in the IL-3 receptor alpha subunit gene.

Interleukin-3 (IL-3) alone does not support hematopoietic colony formation of bone marrow cells from the A/J mouse. To elucidate the molecular lesion in A/J mice, we examined expression of the alpha and beta subunits of the IL-3 receptor (IL-3R). While IL-3R beta was normally expressed, IL-3R alpha...

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Bibliografiska uppgifter
Huvudupphovsmän: Ichihara, M, Hara, T, Takagi, M, Cho, L C, Gorman, D M, Miyajima, A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC398166/
https://ncbi.nlm.nih.gov/pubmed/7889941
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