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Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53.

The tumor suppressor gene product p53 plays an important role in the cellular response to DNA damage from exogenous chemical and physical mutagens. Therefore, we hypothesized that p53 performs a similar role in response to putative endogenous mutagens, such as nitric oxide (NO). We report here that...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Forrester, K, Ambs, S, Lupold, S E, Kapust, R B, Spillare, E A, Weinberg, W C, Felley-Bosco, E, Wang, X W, Geller, D A, Tzeng, E, Billiar, T R, Harris, C C
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39816/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8637893/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.6.2442
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