Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53.

The tumor suppressor gene product p53 plays an important role in the cellular response to DNA damage from exogenous chemical and physical mutagens. Therefore, we hypothesized that p53 performs a similar role in response to putative endogenous mutagens, such as nitric oxide (NO). We report here that...

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Main Authors: Forrester, K, Ambs, S, Lupold, S E, Kapust, R B, Spillare, E A, Weinberg, W C, Felley-Bosco, E, Wang, X W, Geller, D A, Tzeng, E, Billiar, T R, Harris, C C
格式: Artigo
語言:Inglês
出版: 1996
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC39816/
https://ncbi.nlm.nih.gov/pubmed/8637893
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