GATA1 and YY1 are developmental repressors of the human epsilon-globin gene.

The human epsilon-globin gene is transcribed in erythroid cells only during the embryonic stages of development. Expression of epsilon-globin gene, however, can be maintained in adult transgenic mice following removal of DNA positioned between -467 and -182 bp upstream of the epsilon-globin cap site...

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Main Authors: Raich, N, Clegg, C H, Grofti, J, Roméo, P H, Stamatoyannopoulos, G
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC398146/
https://ncbi.nlm.nih.gov/pubmed/7882983
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