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Exonuclease hDIS3L2 specifies an exosome-independent 3′-5′ degradation pathway of human cytoplasmic mRNA
Turnover of mRNA in the cytoplasm of human cells is thought to be redundantly conducted by the monomeric 5′-3′ exoribonuclease hXRN1 and the 3′-5′ exoribonucleolytic RNA exosome complex. However, in addition to the exosome-associated 3′-5′ exonucleases hDIS3 and hDIS3L, the human genome encodes anot...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
European Molecular Biology Organization
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3981170/ https://ncbi.nlm.nih.gov/pubmed/23756462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.135 |
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