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Exonuclease hDIS3L2 specifies an exosome-independent 3′-5′ degradation pathway of human cytoplasmic mRNA

Turnover of mRNA in the cytoplasm of human cells is thought to be redundantly conducted by the monomeric 5′-3′ exoribonuclease hXRN1 and the 3′-5′ exoribonucleolytic RNA exosome complex. However, in addition to the exosome-associated 3′-5′ exonucleases hDIS3 and hDIS3L, the human genome encodes anot...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lubas, Michal, Damgaard, Christian K, Tomecki, Rafal, Cysewski, Dominik, Jensen, Torben Heick, Dziembowski, Andrzej
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: European Molecular Biology Organization 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981170/
https://ncbi.nlm.nih.gov/pubmed/23756462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.135
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