Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

Delivery of granule contents to epithelial surfaces by secretory cells is a critical physiologic process. In the intestine, goblet cells secrete mucus that is required for homeostasis. Autophagy proteins are required for secretion in some cases, though the mechanism and cell biological basis for thi...

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Main Authors: Patel, Khushbu K, Miyoshi, Hiroyuki, Beatty, Wandy L, Head, Richard D, Malvin, Nicole P, Cadwell, Ken, Guan, Jun-Lin, Saitoh, Tatsuya, Akira, Shizuo, Seglen, Per O, Dinauer, Mary C, Virgin, Herbert W, Stappenbeck, Thaddeus S
Formato: Artigo
Idioma:Inglês
Publicado: European Molecular Biology Organization 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981139/
https://ncbi.nlm.nih.gov/pubmed/24185898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.233
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