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Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

Delivery of granule contents to epithelial surfaces by secretory cells is a critical physiologic process. In the intestine, goblet cells secrete mucus that is required for homeostasis. Autophagy proteins are required for secretion in some cases, though the mechanism and cell biological basis for thi...

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Detalhes bibliográficos
Main Authors: Patel, Khushbu K, Miyoshi, Hiroyuki, Beatty, Wandy L, Head, Richard D, Malvin, Nicole P, Cadwell, Ken, Guan, Jun-Lin, Saitoh, Tatsuya, Akira, Shizuo, Seglen, Per O, Dinauer, Mary C, Virgin, Herbert W, Stappenbeck, Thaddeus S
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981139/
https://ncbi.nlm.nih.gov/pubmed/24185898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.233
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