Transcription-coupled repair removes both cyclobutane pyrimidine dimers and 6-4 photoproducts with equal efficiency and in a sequential way from transcribed DNA in xeroderma pigmentosum group C fibroblasts.

We investigated the contribution of the global and the transcription-coupled nucleotide excision repair pathway to the removal of structurally different DNA lesions. The repair kinetics of UV-induced cyclobutane pyrimidine dimers (CPDs) and pyrimidine (6-4) pyrimidone photoproducts (6-4PPs) were det...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: van Hoffen, A, Venema, J, Meschini, R, van Zeeland, A A, Mullenders, L H
Format: Artigo
Langue:Inglês
Publié: 1995
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC398090/
https://ncbi.nlm.nih.gov/pubmed/7835346
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