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Transcription-coupled repair removes both cyclobutane pyrimidine dimers and 6-4 photoproducts with equal efficiency and in a sequential way from transcribed DNA in xeroderma pigmentosum group C fibroblasts.

We investigated the contribution of the global and the transcription-coupled nucleotide excision repair pathway to the removal of structurally different DNA lesions. The repair kinetics of UV-induced cyclobutane pyrimidine dimers (CPDs) and pyrimidine (6-4) pyrimidone photoproducts (6-4PPs) were det...

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書目詳細資料
發表在:EMBO J
Principais autores: van Hoffen, A, Venema, J, Meschini, R, van Zeeland, A A, Mullenders, L H
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 1995
主題:
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398090/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7835346/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07010.x
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