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Structural Perspective on Enzymatic Halogenation

[Image: see text] Simple halogen substituents frequently afford key structural features that account for the potency and selectivity of natural products, including antibiotics and hormones. For example, when a single chlorine atom on the antibiotic vancomycin is replaced by hydrogen, the resulting a...

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Autori principali: Blasiak, Leah C., Drennan, Catherine L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2008
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980734/
https://ncbi.nlm.nih.gov/pubmed/18774824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar800088r
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