CHIP-BASED DIRECT GENOTYPING OF CODING VARIANTS IN GENOME WIDE ASSOCIATION STUDIES: UTILITY, ISSUES AND PROSPECTS

There is considerable debate about the most efficient way to interrogate rare coding variants in association studies. The options include direct genotyping of specific known coding variants in genes or, alternatively, sequencing across the entire exome to capture known as well as novel variants. Eac...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nievergelt, Caroline M., Wineinger, Nathan E., Libiger, Ondrej, Pham, Phillip, Zhang, Guangfa, Baker, Dewleen G., Schork, Nicholas J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980715/
https://ncbi.nlm.nih.gov/pubmed/24521671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2014.01.069
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