Nonshivering thermogenesis protects against defective calcium handling in muscle

When acutely exposed to a cold environment, mammals shiver to generate heat. During prolonged cold exposure, shivering is replaced by adaptive adrenergic nonshivering thermogenesis with increased heat production in brown adipose tissue due to activation of uncoupling protein-1 (UCP1). This cold accl...

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Bibliografiske detaljer
Main Authors: Aydin, Jan, Shabalina, Irina G., Place, Nicolas, Reiken, Steven, Zhang, Shi-Jin, Bellinger, Andrew M., Nedergaard, Jan, Cannon, Barbara, Marks, Andrew R., Bruton, Joseph D., Westerblad, Håkan
Format: Artigo
Sprog:Inglês
Udgivet: The Federation of American Societies for Experimental Biology 2008
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980658/
https://ncbi.nlm.nih.gov/pubmed/18687806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-113712
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