Nonshivering thermogenesis protects against defective calcium handling in muscle

When acutely exposed to a cold environment, mammals shiver to generate heat. During prolonged cold exposure, shivering is replaced by adaptive adrenergic nonshivering thermogenesis with increased heat production in brown adipose tissue due to activation of uncoupling protein-1 (UCP1). This cold accl...

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Detalhes bibliográficos
Main Authors: Aydin, Jan, Shabalina, Irina G., Place, Nicolas, Reiken, Steven, Zhang, Shi-Jin, Bellinger, Andrew M., Nedergaard, Jan, Cannon, Barbara, Marks, Andrew R., Bruton, Joseph D., Westerblad, Håkan
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2008
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980658/
https://ncbi.nlm.nih.gov/pubmed/18687806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-113712
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