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Thrombin receptor and RhoA mediate cell proliferation through integrins and cysteine-rich protein 61
A subset of G-protein coupled receptors (GPCRs), including the thrombin receptor (PAR1), elicits mitogenic responses. Thrombin also activates Ras homolog gene family member A (RhoA) and activating protein (AP-1) -mediated gene expression in 1321N1 astrocytoma cells, whereas the nonmitogenic agonist...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Federation of American Societies for Experimental Biology
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3980657/ https://ncbi.nlm.nih.gov/pubmed/18687805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-113266 |
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