Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages

During helminth infections, alternatively activated macrophages (AAMacs) are key to promoting Th2 responses and suppressing Th1-driven inflammatory pathology. Th2 cytokines IL-4 and/or IL-13 are believed to be important in the induction and activation of AAMacs. Using murine models for the helminth...

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Detalhes bibliográficos
Main Authors: Donnelly, Sheila, Stack, Colin M., O'Neill, Sandra M., Sayed, Ahmed A., Williams, David L., Dalton, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2008
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980656/
https://ncbi.nlm.nih.gov/pubmed/18708590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-106278
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