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RPA Antagonizes Microhomology-Mediated Repair of DNA Double-Strand Breaks
Microhomology-mediated end joining (MMEJ) is a Ku and Ligase IV independent mechanism for repair of DNA double-strand breaks, which contributes to chromosome rearrangements. Here we used a chromosomal end-joining assay to determine the genetic requirements for MMEJ in Saccharomyces cerevisiae. We fo...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3980576/ https://ncbi.nlm.nih.gov/pubmed/24608368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2786 |
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