NF-E2 and GATA binding motifs are required for the formation of DNase I hypersensitive site 4 of the human beta-globin locus control region.

The beta-like globin genes require the upstream locus control region (LCR) for proper expression. The active elements of the LCR coincide with strong erythroid-specific DNase I-hypersensitive sites (HSs). We have used 5' HS4 as a model to study the formation of these HSs. Previously, we identified a...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Stamatoyannopoulos, J A, Goodwin, A, Joyce, T, Lowrey, C H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398057/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7828582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb06980.x
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