An albumin leader sequence coupled with a cleavage site modification enhances the yield of recombinant C-terminal Mullerian Inhibiting Substance

Mullerian Inhibiting Substance (MIS) has been shown to inhibit ovarian cancer cells both in-vitro and in-vivo. Furthermore, recent evidence suggests that MIS may effectively target a putative ovarian cancer progenitor cell population enriched by a panel of CD44+, CD24+, Ep-CAM+, and E-cadherin-cell...

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Main Authors: Pépin, D., Hoang, M., Nicolaou, F., Hendren, K., Benedict, L.A., Al-Moujahed, A., Sosulski, A., Marmalidou, A., Vavvas, D., Donahoe, P.K.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980489/
https://ncbi.nlm.nih.gov/pubmed/24729676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1142/S2339547813500076
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