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Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders.

Mice homozygous for lpr (lymphoproliferation) or gld (generalized lymphoproliferative disease) develop lymphadenopathy and splenomegaly and suffer from autoimmune disease. The lpr mice have a defect in a cell-surface receptor, Fas, that mediates apoptosis, while gld mice have a mutation in the Fas l...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Watanabe, D, Suda, T, Hashimoto, H, Nagata, S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1995
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC398047/
https://ncbi.nlm.nih.gov/pubmed/7530197
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