Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders.

Mice homozygous for lpr (lymphoproliferation) or gld (generalized lymphoproliferative disease) develop lymphadenopathy and splenomegaly and suffer from autoimmune disease. The lpr mice have a defect in a cell-surface receptor, Fas, that mediates apoptosis, while gld mice have a mutation in the Fas l...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Watanabe, D, Suda, T, Hashimoto, H, Nagata, S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 1995
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398047/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7530197/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb06970.x
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