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‘Reduced malignancy as a mechanism for longevity in mice with adenylyl cyclase type 5 disruption’

Disruption of adenylyl cyclase type 5 (AC5) knockout (KO) is a novel model for longevity. Because malignancy is a major cause of death and reduced lifespan in mice, the goal of this investigation was to examine the role of AC5KO in protecting against cancer. There have been numerous discoveries in g...

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Detalhes bibliográficos
Main Authors: De Lorenzo, Mariana S, Chen, Wen, Baljinnyam, Erdene, Carlini, María J, La Perle, Krista, Bishop, Sanford P, Wagner, Thomas E, Rabson, Arnold B, Vatner, Dorothy E, Puricelli, Lydia I, Vatner, Stephen F
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980454/
https://ncbi.nlm.nih.gov/pubmed/23957304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12152
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