Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity

Despite progress in defining human leukocyte antigen (HLA) alleles for anti-citrullinated-protein-autoantibody-positive (ACPA(+)) rheumatoid arthritis (RA), identifying HLA alleles for ACPA-negative (ACPA(−)) RA has been challenging because of clinical heterogeneity within clinical cohorts. We imput...

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Main Authors: Han, Buhm, Diogo, Dorothée, Eyre, Steve, Kallberg, Henrik, Zhernakova, Alexandra, Bowes, John, Padyukov, Leonid, Okada, Yukinori, González-Gay, Miguel A., Rantapää-Dahlqvist, Solbritt, Martin, Javier, Huizinga, Tom W.J., Plenge, Robert M., Worthington, Jane, Gregersen, Peter K., Klareskog, Lars, de Bakker, Paul I.W., Raychaudhuri, Soumya
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980428/
https://ncbi.nlm.nih.gov/pubmed/24656864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2014.02.013
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