Human B Cell-Derived Lymphoblastoid Cell Lines Constitutively Produce Fas Ligand and Secrete MHCII(+)FasL(+) Killer Exosomes

Immune suppression mediated by exosomes is an emerging concept with potentially immense utility for immunotherapy in a variety of inflammatory contexts, including allogeneic transplantation. Exosomes containing the apoptosis-inducing molecule Fas ligand (FasL) have demonstrated efficacy in inhibitin...

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Detalhes bibliográficos
Main Authors: Klinker, Matthew W., Lizzio, Vincent, Reed, Tamra J., Fox, David A., Lundy, Steven K.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980107/
https://ncbi.nlm.nih.gov/pubmed/24765093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00144
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