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Gerometabolites: The pseudohypoxic aging side of cancer oncometabolites

Oncometabolites are defined as small-molecule components (or enantiomers) of normal metabolism whose accumulation causes signaling dysregulation to establish a milieu that initiates carcinogenesis. In a similar manner, we propose the term “gerometabolites” to refer to small-molecule components of no...

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Bibliographic Details
Main Authors: Menendez, Javier A, Alarcón, Tomás, Joven, Jorge
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979906/
https://ncbi.nlm.nih.gov/pubmed/24526120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28079
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