Antiproliferative efficacies but minor drug transporter inducing effects of paclitaxel, cisplatin, or 5-fluorouracil in a murine xenograft model for head and neck squamous cell carcinoma

Drug-induced multidrug resistance (MDR) has been linked to overexpression of drug transporting proteins in head and neck squamous cell carcinoma (HNSCC) in vitro. The aim of this work was to reassess these findings in a murine xenograft model. NOD-SCID mice xenotransplanted with 10(6) HNO97 cells we...

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Detalhes bibliográficos
Main Authors: Theile, Dirk, Gal, Zoltan, Warta, Rolf, Rigalli, Juan Pablo, Lahrmann, Bernd, Grabe, Niels, Herold-Mende, Christel, Dyckhoff, Gerhard, Weiss, Johanna
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979821/
https://ncbi.nlm.nih.gov/pubmed/24448417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27632
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