Antiproliferative efficacies but minor drug transporter inducing effects of paclitaxel, cisplatin, or 5-fluorouracil in a murine xenograft model for head and neck squamous cell carcinoma

Drug-induced multidrug resistance (MDR) has been linked to overexpression of drug transporting proteins in head and neck squamous cell carcinoma (HNSCC) in vitro. The aim of this work was to reassess these findings in a murine xenograft model. NOD-SCID mice xenotransplanted with 10(6) HNO97 cells we...

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Détails bibliographiques
Auteurs principaux: Theile, Dirk, Gal, Zoltan, Warta, Rolf, Rigalli, Juan Pablo, Lahrmann, Bernd, Grabe, Niels, Herold-Mende, Christel, Dyckhoff, Gerhard, Weiss, Johanna
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2014
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979821/
https://ncbi.nlm.nih.gov/pubmed/24448417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27632
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