MicroRNA-148b and microRNA-152 reactivate tumor suppressor genes through suppression of DNA methyltransferase-1 gene in pancreatic cancer cell lines

Overexpression of DNA methyltransferase 1 (DNMT-1) is observed mostly in pancreatic cancer and it can cause tumor suppressor genes silencing in this disease. Recent studies suggest that abnormal expressions of microRNAs (miRs) are involved in pathogenesis of different types of human cancers includin...

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Autores principales: Azizi, Masoumeh, Teimoori-Toolabi, Ladan, Arzanani, Mohsen Karimi, Azadmanesh, Kayhan, Fard-Esfahani, Pezhman, Zeinali, Sirous
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2014
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979819/
https://ncbi.nlm.nih.gov/pubmed/24448385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27630
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