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MicroRNA-148b and microRNA-152 reactivate tumor suppressor genes through suppression of DNA methyltransferase-1 gene in pancreatic cancer cell lines

Overexpression of DNA methyltransferase 1 (DNMT-1) is observed mostly in pancreatic cancer and it can cause tumor suppressor genes silencing in this disease. Recent studies suggest that abnormal expressions of microRNAs (miRs) are involved in pathogenesis of different types of human cancers includin...

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מידע ביבליוגרפי
Main Authors: Azizi, Masoumeh, Teimoori-Toolabi, Ladan, Arzanani, Mohsen Karimi, Azadmanesh, Kayhan, Fard-Esfahani, Pezhman, Zeinali, Sirous
פורמט: Artigo
שפה:Inglês
יצא לאור: Landes Bioscience 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979819/
https://ncbi.nlm.nih.gov/pubmed/24448385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27630
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