MicroRNA-148b and microRNA-152 reactivate tumor suppressor genes through suppression of DNA methyltransferase-1 gene in pancreatic cancer cell lines

Overexpression of DNA methyltransferase 1 (DNMT-1) is observed mostly in pancreatic cancer and it can cause tumor suppressor genes silencing in this disease. Recent studies suggest that abnormal expressions of microRNAs (miRs) are involved in pathogenesis of different types of human cancers includin...

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Bibliographische Detailangaben
Hauptverfasser: Azizi, Masoumeh, Teimoori-Toolabi, Ladan, Arzanani, Mohsen Karimi, Azadmanesh, Kayhan, Fard-Esfahani, Pezhman, Zeinali, Sirous
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979819/
https://ncbi.nlm.nih.gov/pubmed/24448385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27630
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