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Targeted Delivery of Doxorubicin-Loaded Poly (ε-caprolactone)-b-Poly (N-vinylpyrrolidone) Micelles Enhances Antitumor Effect in Lymphoma

BACKGROUND: The present study was motivated by the need to design a safe nano-carrier for the delivery of doxorubicin which could be tolerant to normal cells. PCL(63)-b-PNVP(90) was loaded with doxorubicin (6 mg/ml), and with 49.8% drug loading efficiency; it offers a unique platform providing selec...

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Detalhes bibliográficos
Main Authors: Hira, Sumit Kumar, Mishra, Avnish Kumar, Ray, Biswajit, Manna, Partha Pratim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979807/
https://ncbi.nlm.nih.gov/pubmed/24714166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094309
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