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Synergistic and Antagonistic Drug Combinations Depend on Network Topology

Drug combinations may exhibit synergistic or antagonistic effects. Rational design of synergistic drug combinations remains a challenge despite active experimental and computational efforts. Because drugs manifest their action via their targets, the effects of drug combinations should depend on the...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Yin, Ning, Ma, Wenzhe, Pei, Jianfeng, Ouyang, Qi, Tang, Chao, Lai, Luhua
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979733/
https://ncbi.nlm.nih.gov/pubmed/24713621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093960
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