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Synergistic and Antagonistic Drug Combinations Depend on Network Topology
Drug combinations may exhibit synergistic or antagonistic effects. Rational design of synergistic drug combinations remains a challenge despite active experimental and computational efforts. Because drugs manifest their action via their targets, the effects of drug combinations should depend on the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979733/ https://ncbi.nlm.nih.gov/pubmed/24713621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093960 |
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