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Amyloid plaque core protein in Alzheimer disease and Down syndrome.

We have purified and characterized the cerebral amyloid protein that forms the plaque core in Alzheimer disease and in aged individuals with Down syndrome. The protein consists of multimeric aggregates of a polypeptide of about 40 residues (4 kDa). The amino acid composition, molecular mass, and NH2...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Masters, C L, Simms, G, Weinman, N A, Multhaup, G, McDonald, B L, Beyreuther, K
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1985
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Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397973/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3159021/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.12.4245
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