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Amyloid plaque core protein in Alzheimer disease and Down syndrome.
We have purified and characterized the cerebral amyloid protein that forms the plaque core in Alzheimer disease and in aged individuals with Down syndrome. The protein consists of multimeric aggregates of a polypeptide of about 40 residues (4 kDa). The amino acid composition, molecular mass, and NH2...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1985
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397973/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3159021/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.12.4245 |
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