Llwytho...

Preexisting high frequencies of memory CD8(+) T cells favors rapid memory differentiation and preservation of proliferative potential upon boosting

Memory CD8(+) T cell quantity and quality determine protective efficacy against reinfection. Heterologous prime boost vaccination minimizes contraction of anamnestic effectors and maximizes memory CD8(+) T cell quantity, but reportedly erodes proliferative potential and protective efficacy. This stu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fraser, Kathryn A., Schenkel, Jason M., Jameson, Stephen C., Vezys, Vaiva, Masopust, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979587/
https://ncbi.nlm.nih.gov/pubmed/23890070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.07.003
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!