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Genetic discoveries in AD using CSF amyloid and tau

The use of cerebrospinal fluid levels of Aβ42 and pTau181 as endophenotypes for genetic studies of Alzheimer's disease (AD) has led to successful identification of both rare and common AD risk variants. In addition, this approach has provided meaningful hypotheses for the biological mechanisms...

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Detalhes bibliográficos
Main Authors: Cruchaga, Carlos, Ebbert, Mark T. W., Kauwe, John S. K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979575/
https://ncbi.nlm.nih.gov/pubmed/24729949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40142-014-0031-0
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