Molecular properties and fibril ultrastructure of types II and XI collagens in cartilage of mice expressing exclusively the α1(IIA) collagen isoform

Until now, no biological tools have been available to determine if a cross-linked collagen fibrillar network derived entirely from type IIA procollagen isoforms, can form in the extracellular matrix (ECM) of cartilage. Recently, homozygous knock-in transgenic mice (Col2a1(+ex2), ki/ki) were generate...

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Hauptverfasser: McAlinden, Audrey, Traeger, Geoffrey, Hansen, Uwe, Weis, Mary Ann, Ravindran, Soumya, Wirthlin, Louisa, Eyre, David R., Fernandes, Russell J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979507/
https://ncbi.nlm.nih.gov/pubmed/24113490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2013.09.006
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