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Genetic variation of a bacterial pathogen within individuals with cystic fibrosis provides a record of selective pressures
Advances in sequencing have enabled the identification of mutations acquired by bacterial pathogens during infection(1-10). However, it remains unclear whether adaptive mutations fix in the population or lead to pathogen diversification within the patient(11,12). Here, we study the genotypic diversi...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979468/ https://ncbi.nlm.nih.gov/pubmed/24316980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2848 |
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