Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes

Bacterial pathogens evolve during the infection of their human hosts(1-8), but separating adaptive and neutral mutations remains challenging(9-11). Here, we identify bacterial genes under adaptive evolution by tracking recurrent patterns of mutations in the same pathogenic strain during the infectio...

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Detalhes bibliográficos
Main Authors: Lieberman, Tami D., Michel, Jean-Baptiste, Aingaran, Mythili, Potter-Bynoe, Gail, Roux, Damien, Davis, Michael R., Skurnik, David, Leiby, Nicholas, LiPuma, John J., Goldberg, Joanna B., McAdam, Alexander J., Priebe, Gregory P., Kishony, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245322/
https://ncbi.nlm.nih.gov/pubmed/22081229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.997
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