Targeting Pan-Resistant Bacteria With Antibodies to a Broadly Conserved Surface Polysaccharide Expressed During Infection

BACKGROUND: New therapeutic targets for antibiotic-resistant bacterial pathogens are desperately needed. The bacterial surface polysaccharide poly-β-(1-6)-N-acetyl-glucosamine (PNAG) mediates biofilm formation by some bacterial species, and antibodies to PNAG can confer protective immunity. By analy...

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Bibliografische gegevens
Hoofdauteurs: Skurnik, David, Davis, Michael R., Benedetti, Dennis, Moravec, Katie L., Cywes-Bentley, Colette, Roux, Damien, Traficante, David C., Walsh, Rebecca L., Maira-Litràn, Tomas, Cassidy, Sara K., Hermos, Christina R., Martin, Thomas R., Thakkallapalli, Erin L., Vargas, Sara O., McAdam, Alexander J., Lieberman, Tami D., Kishony, Roy, LiPuma, John J., Pier, Gerald B., Goldberg, Joanna B., Priebe, Gregory P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2012
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Major Articles and Brief Reports
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415848/
https://ncbi.nlm.nih.gov/pubmed/22448004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis254
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