CD36- and GPR120-mediated Ca(2+) Signaling in Human Taste Bud Cells Mediates Differential Responses to Fatty Acids and is Altered in Obese Mice

BACKGROUND & AIMS: It is important to increase our understanding of gustatory detection of dietary fat and its contribution to fat preference. We studied the roles of the fat taste receptors CD36 and GPR120 and their interactions via Ca(2+) signaling in fungiform taste bud cells (TBC). METHODS:...

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Huvudupphovsmän: Ozdener, Mehmet Hakan, Subramaniam, Selvakumar, Sundaresan, Sinju, Sery, Omar, Hashimoto, Toshihiro, Asakawa, Yoshinori, Besnard, Philippe, Abumrad, Nada A., Khan, Naim Akhtar
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979457/
https://ncbi.nlm.nih.gov/pubmed/24412488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.01.006
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