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Generation of a humanized mouse model with both human immune system and liver cells to model hepatitis C virus infection and liver immunopathogenesis

Establishing a small animal model that accurately recapitulates hepatotropic pathogens, including hepatitis C virus (HCV) infection and immunopathogenesis, is essential for the study of hepatitis virus–induced liver disease and for therapeutics development. This protocol describes our recently devel...

詳細記述

保存先:
書誌詳細
主要な著者: Bility, Moses T, Zhang, Liguo, Washburn, Michael L, Curtis, T Anthony, Kovalev, Grigoriy I, Su, Lishan
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979325/
https://ncbi.nlm.nih.gov/pubmed/22899330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2012.083
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