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Sleep and Alzheimer disease pathology—a bidirectional relationship

Factors other than age and genetics may increase the risk of developing Alzheimer disease (AD). Accumulation of the amyloid-β (Aβ) peptide in the brain seems to initiate a cascade of key events in the pathogenesis of AD. Moreover, evidence is emerging that the sleep–wake cycle directly influences le...

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Hlavní autoři: Ju, Yo-El S., Lucey, Brendan P., Holtzman, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979317/
https://ncbi.nlm.nih.gov/pubmed/24366271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneurol.2013.269
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