Lenalidomide (Revlimid(®)) administration at symptom onset is neuroprotective in a mouse model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease which is currently untreatable. Inflammation plays a major role in the pathogenesis of motor neuron death in ALS. Pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and Fas ligand (FasL) are amongst the most imp...

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Hlavní autoři: Neymotin, Arie, Petri, Susanne, Calingasan, Noel Y., Wille, Elizabeth, Schafer, Peter, Stewart, Charles, Hensley, Kenneth, Beal, M. Flint, Kiaei, Mahmoud
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979314/
https://ncbi.nlm.nih.gov/pubmed/19733563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.08.028
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