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Lenalidomide (Revlimid(®)) administration at symptom onset is neuroprotective in a mouse model of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease which is currently untreatable. Inflammation plays a major role in the pathogenesis of motor neuron death in ALS. Pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and Fas ligand (FasL) are amongst the most imp...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979314/ https://ncbi.nlm.nih.gov/pubmed/19733563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.08.028 |
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