Is there a single pathway for the folding of a polypeptide chain?
We argue that folding of the compact domains of proteins can occur with adequate rapidity in the absence of a unique directed mechanism, provided that native-like local structure dominates the folding process. We further suggest that the evolution of amino acid sequences should favor multiple paths...
Tallennettuna:
| Julkaisussa: | Proc Natl Acad Sci U S A |
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| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
1985
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3858860/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.12.4028 |
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