Vaccines against human HER2 prevent mammary carcinoma in mice transgenic for human HER2

INTRODUCTION: The availability of mice transgenic for the human HER2 gene (huHER2) and prone to the development of HER2-driven mammary carcinogenesis (referred to as FVB-huHER2 mice) prompted us to study active immunopreventive strategies targeting the human HER2 molecule in a tolerant host. METHODS...

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Main Authors: De Giovanni, Carla, Nicoletti, Giordano, Quaglino, Elena, Landuzzi, Lorena, Palladini, Arianna, Ianzano, Marianna Lucia, Dall’Ora, Massimiliano, Grosso, Valentina, Ranieri, Dario, Laranga, Roberta, Croci, Stefania, Amici, Augusto, Penichet, Manuel L, Iezzi, Manuela, Cavallo, Federica, Nanni, Patrizia, Lollini, Pier-Luigi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979148/
https://ncbi.nlm.nih.gov/pubmed/24451168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3602
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