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Effect of sclerostin-neutralising antibody on periarticular and systemic bone in a murine model of rheumatoid arthritis: a microCT study

INTRODUCTION: Patients with chronic inflammatory diseases have increased bone loss and bone fragility and are at increased risk of fracture. Although anti-resorptive drugs are effective in blocking inflammation-induced bone loss, they are less effective at rebuilding bone. We have previously shown t...

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Hlavní autoři: Marenzana, Massimo, Vugler, Alex, Moore, Adrian, Robinson, Martyn
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979059/
https://ncbi.nlm.nih.gov/pubmed/24432364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4305
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